Clinton Warns Syria Against Using Chemical Weapons

Narciso Contreras/Associated Press

 A kitchen in a home in Aleppo, Syria showed signs of heavy fighting Sunday.

WASHINGTON — President Obama warned Syria’s government on Monday that it would be “totally unacceptable” to use chemical weapons against its own people and vowed to hold accountable anyone who did, as American intelligence officials picked up signs that such arms might be deployed in the ongoing insurgency.

The White House said that some recent actions by the government of President Bashar al-Assad were indicators that Syrian forces were preparing to use such weapons, following earlier reports that intelligence agencies had noticed signs of activity at chemical weapons sites. Mr. Obama’s spokesman said the administration had “an increased concern” of possible use of chemical weapons.

In a speech later in the day that echoed earlier comments by Secretary of State Hillary Rodham Clinton, Mr. Obama sternly asserted again that he would punish Syria for using chemical weapons, although he did not say how. The administration has been preparing contingency plans that include the dispatch of tens of thousands of troops to secure such weapons, although it is not clear whether Mr. Obama would go that far.

“Today I want to make it absolutely clear to Assad and those under his command: The world is watching,” Mr. Obama said in a speech at the National Defense University in Washington. “The use of chemical weapons is and would be totally unacceptable. If you make the tragic mistake of using these weapons, there will be consequences and you will be held accountable.”

During an earlier briefing at the White House, Jay Carney, the president’s press secretary, hinted at possible military action in response, although he declined to specify what options Mr. Obama would consider. “We think it is important to prepare for all scenarios,” Mr. Carney said. “Contingency planning is the responsible thing to do.”

The president’s statements on Syria amplified similar warnings issued by Mrs. Clinton earlier in the day in Prague, the Czech capital, where she was stopping on her way to meetings in Brussels.

“This is a red line for the United States,” Mrs. Clinton said, using the same language that the White House later would use. “I am not going to telegraph in any specifics what we would do in the event of credible evidence that the Assad regime has resorted to using chemical weapons against their own people. But suffice it to say we are certainly planning to take action if that eventuality were to occur.”

There have been signs in recent days of heightened activity at some of Syria’s chemical weapons sites, according to American and Israeli officials familiar with intelligence reports. Mrs. Clinton did not confirm the intelligence reports or say what sort of activity was occurring.

The Syrian Foreign Ministry, in a swift response, said the government “would not use chemical weapons, if it had them, against its own people under any circumstances.” The statement was reported on Syrian state television and on the Lebanese channel LBC.

The crisis has been worsening in Syria, where about 40,000 people have been killed in 20 months of conflict that has also spilled into neighboring countries. The warning from the White House came as developments elsewhere suggested the political terrain could be shifting.

The spokesman for Syria’s foreign ministry, Jihad Makdissi, was reported by the Hezbollah-run television station, Al Manar, as having been fired, although Lebanese news Web sites reported the departure as a defection. Mr. Makdissi, one of the highest ranking Christians to defect, had been one of the most accessible Syrian officials for foreign journalists. Al Manar reported that he was fired for making statements that did not reflect the government’s point of view, though it was unclear what those statements might have been.

But in recent months he had not taken phone calls and had not made public statements, leading some to speculate that he had either fallen out of favor or had doubts about the government. A security source said Mr. Makdissi flew to London from Beirut on Monday morning with his family.

Michael R. Gordon reported from Brussels. Reporting contributed by Anne Barnard from Beirut, Lebanon, and Sebnem Arsu from Istanbul.

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Four Things Google’s Nexus 4 Has in Common with the iPhone 4

Besides being each company’s flagship smartphone (and having the number 4 in their names), Google‘s new Nexus 4 and the 2010 iPhone 4 have a fair bit in common with each other.

This could be a good thing, if you remember just how popular the iPhone 4 was. Unfortunately, in this case it’s more of a bad thing, and hearkens back to “Antennagate” and the iPhone 4′s other problems. Do any of these features remind you of anything?

​A glass back

With the iPhone 5, Apple finally moved from a crack- and scratch-prone glass backplate to a solid, aluminum unibody construction. Google doesn’t seem to have gotten the memo that the former may have been a bad idea, however, and the Nexus 4 has a sparkly glass back surface.

While sparkly things obviously have their fans, the Nexus 4′s chassis also seems to lean towards the brittle side. Joshua Topolsky, who reviewed the Nexus 4 for The Verge, managed to crack the glass when he accidentally knocked his phone off the table. Meanwhile, Droid-Life’s Kellex found that setting the phone on a stone countertop caused its glass back to fracture in two.

​No 4G

Even Topolsky’s glowing review of the Nexus 4 said “It feels slow,” and “There’s simply no way to ignore this deficit.” That’s because, like the iPhone 4, the Nexus 4 lacks a 4G radio (even though it has the chip to support one if it had it).

The iPhone 4, however, was released in 2010, when 4G was still a new thing and the Android “superphones” which supported it had enormous screens and horrible battery life. Today, even the iPhone has 4G. Possibly because of bad blood between Google and the wireless carriers, which appear to resent Google’s selling phones unsubsidized and sans “customizations,” the Nexus 4 does not.

​Selling out fast

Every one of Apple’s iPhone models has sold out faster, and more dramatically, than the one before. Google’s Android devices, in contrast, haven’t tended to do so … although the new Nexus smartphones and tablets are starting to have this problem.

How bad is it? After Google finally got a new wave of Nexus 4s up for sale, they sold out in about a half-hour. Google claims that it hasn’t actually sold out, but even if you spotted the Nexus 4 on Google Play, chances are you ran into technical glitches which kept it out of your shopping cart. Tipster “Syko Pompos” told the Android Police blog how to get around this and place your order, but expect to wait months to receive it.

​Public relations nightmares

It hasn’t quite reached Antennagate levels yet, perhaps partly because the Nexus brand isn’t as well-known as the iPhone (the iPhone 4′s antenna problems were actually shared by many smartphones). But most of the press coverage of the Nexus 4 lately has been about how you can’t get one. Or else, how if you want one you’ll have to either buy it on contract or pay a lot more to get it unsubsidized from T-Mobile.

On the plus side (for the Nexus), this problem is only partly caused by the Google Play store’s technical errors. The biggest reason it’s taking so long to get out to people is, like with the iPhone 4, simply how popular it is.

Jared Spurbeck is an open-source software enthusiast, who uses an Android phone and an Ubuntu laptop PC. He has been writing about technology and electronics since 2008.

Linux/Open Source News Headlines – Yahoo! News

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Heisman finalists: Manziel, Te'o and Klein

NEW YORK (AP) — Johnny Manziel and Manti Te'o are in position to make Heisman Trophy history.

Manziel, the redshirt freshman quarterback from Texas A&M, and Te'o, Notre Dame's star linebacker, along with Kansas State quarterback Collin Klein, were invited Monday to attend the Heisman presentation ceremony.

Manziel is the favorite to win college football's most famous player of the year award on Saturday night in Manhattan. He would be the first freshman to win the Heisman and the first Texas A&M player since halfback John David Crow won the school's only Heisman in 1957.

"I'm overwhelmed by this tremendous honor of representing Texas A&M, the 12th Man and all my teammates in New York," Manziel said in a statement. "This is a dream come true for me, and I know it's a credit to all my coaches and teammates. I definitely wouldn't be a Heisman finalist without my teammates and coaches."

Three sophomores have won the award (Tim Tebow in 2007, Sam Bradford in 2008 and Mark Ingram in 2009), but the best a first-year player has ever done is second.

Adrian Peterson of Oklahoma finished second to Southern California quarterback Matt Leinart in 2004. Peterson was a true freshman. As a redshirt freshman, Manziel attended A&M last year and practiced with the team but did not play.

Michael Vick of Virginia Tech came in third in 1999 as a redshirt freshman and Herschel Walker was a true freshman for Georgia in 1980 when he finished third in the Heisman balloting.

Nicknamed Johnny Football, Manziel quickly became a national sensation this season, putting up huge numbers in first-year Texas A&M coach Kevin Sumlin's spread offense. He led the 10th-ranked Aggies to a 10-2 record in their first season in the Southeastern Conference.

With a knack for improvisation, Manziel racked up an SEC-record 4,600 yards of total offense, including 1,181 rushing to lead the conference. The 6-foot-1, 200-pound Manziel zoomed to the front of the Heisman race on Nov. 10, when he passed for 253 yards and two touchdowns and ran for 92 yards as the Aggies upset then-No. 1 Alabama 29-24 in Tuscaloosa.

Manziel and Texas A&M will play No. 12 Oklahoma in the Cotton Bowl.

Te'o is trying to become the first defense-only player to win the Heisman. The Fighting Irish have seven Heisman winners, tied for the most with Ohio State and Southern California, but none since Tim Brown in 1987.

Te'o became the face of the No. 1 team in the country and leader of a defense that has been the toughest to score upon in the nation. The senior intercepted seven passes, second-most in the country and tops for a linebacker. He also led the Fighting Irish with 103 tackles, and earlier Monday won the Butkus Award as country's best linebacker.

Te'o and the Irish face No. 2 Alabama in the BCS championship game on Jan. 7 in Miami.

Klein would be the first player from Kansas State to win the Heisman.

"I'm just honored with this opportunity that the Lord has provided me here at K-State," Klein said in a statement. "I'm so proud to represent K-State in this because I feel like my road is very synonymous and in line with the K-State way. It has been a process, it has been a journey. There have been a lot of ups and downs, as well as a lot of hard times and growing pains through it. I'm just very proud to represent the K-State family and our heart and spirit in this environment."

He seemed to be the front-runner for several weeks until Manziel's late push. When Klein threw three interceptions in the Wildcats' late-season loss to Baylor, Manziel moved to the front of the race.

Klein is a multitalented quarterback like Manziel, but with a different approach. The 6-5, 226-pound senior is a bullish runner who scored 22 touchdowns and threw for 15 more, while leading the seventh-ranked Wildcats (11-1) to the Big 12 title. Earlier in the day, Klein won the Johnny Unitas Award given to the top upperclassman quarterback in the nation.

Klein will finish his Kansas State career against No. 5 Oregon in the Fiesta Bowl.

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Global Update: GlaxoSmithKline Tops Access to Medicines Index

Sang Tan/Associated Press

GlaxoSmithKline hung on to its perennial top spot in the new Access to Medicines Index released last week, but its competitors are closing in.

Every two years, the index ranks the world’s top 20 pharmaceutical companies based on how readily they get medicines they hold patents on to the world’s poor, how much research they do on tropical diseases, how ethically they conduct clinical trials in poor countries, and similar issues.

Johnson & Johnson shot up to second place, while AstraZeneca fell to 16th from 7th. AstraZeneca has had major management shake-ups. It did not do less, but the industry is improving so rapidly that others outscored it, the report said.

The index was greeted with skepticism by some drugmakers when it was introduced in 2008. But now 19 of the 20 companies have a board member or subcommittee tracking how well they do at what the index measures, said David Sampson, the chief author.

The one exception was a Japanese company. As before, Japanese drugmakers ranked at or near the index’s bottom, and European companies clustered near the top. Generic companies — most of them Indian — that export to poor countries are ranked separately.

Johnson & Johnson moved up because it created an access team, disclosed more and bought Crucell, a vaccine company.

The foundation that creates the index now has enough money to continue for five more years, said its founder, Wim Leereveld, a former pharmaceutical executive.

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Deficit Talks Stumble Over Down Payment

WASHINGTON — For all the growing angst over the state of negotiations to head off a fiscal crisis in January, the parties are farthest apart on a relatively small part of the overall deficit reduction program — the down payment.

President Obama and the House speaker, John A. Boehner, are in general agreement that the relevant Congressional committees must sit down next year and work out changes to the tax code and entitlement programs to save well more than $1 trillion over the next decade.

But before that work begins, both men want Congress to approve a first installment on deficit reduction in the coming weeks. The installment would replace the automatic spending cuts and tax increases that make up the “fiscal cliff,” while signaling Washington’s seriousness about getting its fiscal house in order. That is where the chasm lies in size and scope.

Mr. Obama says the down payment should be large and made up almost completely of tax increases on top incomes, partly because he and Congressional leaders last year agreed on some spending cuts over the next decade but have yet to agree on any tax increases.

Republicans have countered by arguing for a smaller down payment that must include immediate savings from Medicare and other social programs. Republicans, using almost mirror-image language, have said that they do not want to agree to specific tax increases and vague promises of future spending cuts.

Senator Kent Conrad of North Dakota, chairman of the Budget Committee and part of a bipartisan “Gang of Six” senators who devised the two-stage process, said: “I think there’s a lot of confusion between the initial down payment and the framework. That’s for sure.”

The two biggest areas of dispute are tax increases and the big government health insurance programs, Medicare and Medicaid. On the health programs, neither side believes Congress could meaningfully overhaul them in the four weeks that remain before the fiscal deadline.

“Entitlement reform is a big step, and it affects tens of millions of people,” said Senator Richard J. Durbin, Democrat of Illinois, another architect of the two-stage framework. “It’s not just a matter of cutting spending in an appropriation. It’s changing policy. And that’s why I was reluctant to include it in the down-payment conversation. I want this to be a thoughtful effort on both sides that doesn’t jeopardize this program.”

But Republicans say that it is possible to make some initial changes to the programs in coming weeks. “There are simpler things that can be done,” said Senator Michael D. Crapo, Republican of Idaho and another Gang of Six member. “The real structural changes would come later.”

Mr. Crapo said Congress could agree on some additional cuts to health care providers and change the way inflation is calculated to slow not only automatic increases in Medicare and Social Security benefits, but also the annual rise in tax brackets.

Democrats instead argue that the down payment should consist of a combination of tax increases and cuts to programs outside Medicare, Medicaid and Social Security, like farm programs. Mr. Obama has pushed for a return to the top tax rates under President Bill Clinton.

Republican leaders have said that they are willing to raise new tax revenues — albeit not as much as Democrats want — but Republicans want taxes to rise by closing loopholes and curbing tax deductions and credits.

If the two sides are able to come to an agreement on the down payment, it would also likely fix targets for larger savings in the tax code and entitlement programs. The White House and Congress would then spend much of the next year trying to hash out the specific policy changes needed to hit those targets.

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Egyptian Court Postpones Ruling on Constitutional Assembly

Wissam Nassar

Egyptian police officers stood guard outside Egypt's Supreme Constitutional Court on Sunday, while supporters of President Mohamed Morsi protested near the entrance of the building.

CAIRO — Egypt’s constitutional court on Sunday put off its much-awaited ruling on the legitimacy of the Islamist-led legislative assembly that drafted a new charter last week, accusing a crowd of Islamists outside the courthouse of intimidating its judges.

What actually took place at the courthouse, however, is a matter of dispute.

Calling Sunday “a dark black day in the history of the Egyptian judiciary,” the Supreme Constitutional Court charged in a statement that a mob of Islamists had blocked the judges from entering the courthouse, in an “abhorrent scene of shame and disgrace.”

Approaching the court, the judges saw crowds “closing the entrances of the roads to the gates, climbing the fences, chanting slogans denouncing judges and inciting the people against them,” the statement said, adding that “the threat of harm” prevented the judges from entering. The judges said they were suspending the court’s sessions until they could resume their work without “psychological and physical pressures.”

While the judges blamed the Islamists, the Islamists accused the judges of manufacturing a melodramatic excuse for failing to show up. And the contradictory narratives captured a clash between the judges — appointed by Hosni Mubarak, the former president — and Egypt’s new Islamist leaders that has thrown the political transition into a new crisis 22 months after Mr. Mubarak’s ouster.

Egyptian courts had previously dissolved both the elected Parliament and an earlier Constitutional Assembly, and the breakup of the current one would have completely undone the transition. President Mohamed Morsi cited the pending ruling on Nov. 22 when he put his own edicts above judicial review until ratification of the constitution, saying that he intended to protect the assembly until it finished its work.

That same apprehension about the ruling drove the assembly to rush to approve a constitution just before dawn on Friday, over the objections of secular parties and the Coptic Christian Church, before the court could act.

The judges’ statement on Sunday was a counterattack, and the scene outside the courthouse was much quieter than their statement described. A line of hundreds of riot police officers backed by a fire truck and several armored personnel carriers were on hand to secure the judges’ entry to the courthouse, and several people were seen coming and going without any difficulty.

The Interior Ministry said in a statement on its Web site that it had arranged to secure the entrance and protect the judges, that the protests were “peaceful,” and that a number of judges had already arrived safely.

On the other side of the police line was a relatively staid crowd of a few hundred demonstrators from the Muslim Brotherhood, Egypt’s mainstream political group, and its political arm, Mr. Morsi’s Freedom and Justice Party. Like many of the group’s demonstrations, it was a mostly middle-aged, middle-class crowd of men in sweaters and a few neckties. By around 10 a.m., some were chanting slogans, but others were sitting on the ground reading newspapers. Many carried placards with Mr. Morsi’s picture or banners with the logo of his party, and one was reading its Web page on his iPad.

“We immunize the constituent assembly, and dissolve the constitutional court,” they chanted. “Freedom is coming, coming.” Some chants were directed at Judge Tahani el-Gebali, who is known for her political activism and opposition to the Islamists.

Magdy Hamed, 47, a businessman and member of the Brotherhood’s party, said the demonstrators had done nothing to stop the judges from entering. “We didn’t stop them,” he said. “We are asking them to come down and do their job.”

Mahmoud el-Akhas, 51, another businessman and party member, interjected, “We are here to exert pressure on the Supreme Constitutional Court to comply with the will of the people.” He reiterated the fears of many Islamists that the court might even seek to annul the presidential decree that granted Mr. Morsi power over the generals who ruled after Mr. Mubarak was ousted.

“The Egyptian people like stability,” Mr. Hamed said. “We don’t want chaos, and we don’t want to start this transition all over again.”

Mayy El Sheikh contributed reporting.

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Here’s How to Turn Nicki Minaj into Jay-Z

We realize there’s only so much time one can spend in a day watching new trailers, viral video clips, and shaky cell phone footage of people arguing on live television. This is why every day The Atlantic Wire highlights the videos that truly earn your five minutes (or less) of attention. Today:

RELATED: It’s Sort of Fun Watching Pippa Middleton Squirm

This is silly, but it’s Friday and a unicorn lair has been found in North Korea, rendering all other silliness moot. But the folks over at Reddit seem to dig the idea of slowing down Nicki Minaj’s songs so much that they sound like an over-enunciating Jay-Z. And well, it’s oddly relaxing: 

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RELATED: The Honey Boo Boo Nature Special; Everyone’s Favorite Sleepwalking Mom

Another week has passed by and we still haven’t figured out the Fiscal Cliff situation. Let’s fix it—and not just because we want to avoid getting downgraded (again). Because honestly, we just don’t think CNBC’s Rick Santelli can make it another two weeks: 

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RELATED: Paul Ryan Was In a Band Called Steak Baby

James Lipton, let’s hang out: 

Finally, it’s Friday. What are you still doing here?  Go enjoy the weekend or something or … watch this video of a husky which sort of sounds like Dame Edna at time imitating a baby until 6 p.m. rolls around: 

Wireless News Headlines – Yahoo! News

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Chiefs beat Panthers at somber Arrowhead Stadium

KANSAS CITY, Mo. (AP) — Romeo Crennel stood in the middle of the Kansas City Chiefs' locker room Sunday, the emotion threatening to overcome the good-natured coach.

Chiefs owner Clark Hunt was at his side, offering support. Members of the team hugged each other, the mud smearing with tears on their cheeks. And over along the wall stood the empty locker that once belonged to Jovan Belcher, his jersey still hanging from a hook.

Just one day after the linebacker killed his girlfriend and then turned the gun on himself, the Chiefs banded together to play their finest game of the season, an inspired 27-21 victory over the Carolina Panthers that ended an eight-game losing streak suddenly rendered trivial.

"As far as playing the game, I thought that was the best for us to do, because that's what we do," Crennel said, tears forming in the corners of his eyes. "We're football players and football coaches and that's what we do, we play on Sunday."

According to authorities, Belcher shot his girlfriend multiple times early Saturday at a residence near Arrowhead Stadium, then sped to the team's practice facility and turn the gun on himself as Crennel and general manager Scott Pioli watched in the parking lot.

Pioli walked through the press box before the game and said he was doing "OK."

"It's been an incredibly difficult 24 hours for our family and our entire organization," Hunt said. "We have so many guys on our team and our coaching staff who are really, really hurting."

Chiefs players gathered in the tunnel leading to the field for a brief prayer before their pregame stretching. A few fans in the half-empty stadium held up signs referencing the shootings, and there was a moment of silence to remember all victims of domestic violence.

Kansas City police have not released a motive for the shootings, which claimed the life of Belcher and 22-year-old Kasandra M. Perkins, and left a 3-month-old girl, Zoey, an orphan.

"I'm just trying to get through the rest of today," said the Chiefs' Brady Quinn, who threw his first two touchdown passes in three years. "The emotions of what has taken place will probably hit home for a few guys the next few days, when they realize what's taken place."

Cam Newton threw for 232 yards and three touchdowns for the Panthers (3-9), who were informed the game would be played as scheduled while they were heading to Kansas City on Saturday.

DeAngelo Williams added 67 yards rushing, carrying the load with Jonathan Stewart out with an injury. Steve Smith, Greg Olsen and Louis Murphy caught Carolina's TD passes.

"You definitely feel for them. What they are going through is tragic," Olsen said. "But we have a job to do. Our job is to come here and prepare to win. They wouldn't expect any less."

Peyton Hillis had a touchdown run for Kansas City (2-10), while Tony Moeaki and Jon Baldwin had touchdown catches. Ryan Succop hit a pair of field goals, including a 52-yarder with 4:54 left that forced the Panthers try for a touchdown to steal the win.

Instead, they went three-and-out, and the Chiefs were able to run the clock down to 31 seconds before giving back the ball. Newton completed two quick passes to reach the Carolina 38, but his final heave as time expired was caught by Smith short of the end zone.

Panthers coach Ron Rivera greeted Crennel at midfield and gave him a hug.

"They played an inspired football game," Rivera said. "They did some really good things, and we have to give them credit, because they suffered through a very difficult time."

The emotions were raw even after the kickoff.

Kansas City took the opening possession and marched 74 yards in just six plays, including a 21-yard pass to Dwayne Bowe and a 34-yarder to Baldwin that got the Chiefs to the Carolina 2.

Hillis powered in to score the first touchdown for Kansas City on the opening possession of a game since Dec. 26, 2010. It was also the first touchdown drive engineered by Quinn since December 2009, when he helped the Browns beat the Chiefs at Arrowhead Stadium.

Hillis ran to the sideline after scoring his first touchdown of the season and handed the ball to Crennel, then gave the guy who managed to hold the team together a hug.

The Panthers answered with a long touchdown drive of their own. The big play came when safety Abe Elam watched Olsen haul in a 47-yard pass from Newton for the tying touchdown.

The Chiefs had tacked on a field goal when the Panthers struck again, this time after Newton completed three passes to convert third downs, the last finding Smith in the end zone.

But Kansas City finished off the half with one of its best drives of the year, an 80-yard march that took up the final 7:25. Hillis was stuffed at the line on third-and-goal, and Crennel allowed the clock to hit 2 seconds before calling timeout. On the final play of the half, Quinn saw Moeaki open in the back of the end zone and delivered a soft toss for a 17-14 lead.

Breathing room came late in the third quarter when the Chiefs used 17 plays to go 87 yards on a drive that lasted another 10 minutes. Quinn finished it with a 3-yard touchdown pass to Baldwin.

Carolina mounted a comeback with the opening drive of the fourth quarter, with Newton hitting Murphy on a quick slant route from the 8 to get the Panthers within a field goal. But the Chiefs added their own field goal, and then burned enough of the clock to ensure the victory.

One that allowed the Chiefs to celebrate in the midst of their mourning.

"There were pockets in the game where reality hits you again, and that's sobering," said Chiefs linebacker Andy Studebaker. "I've been telling people, Jovan was like a brother to us. His family was family to us. Our hearts go out to them, man, and the game maybe took our heads off it for a while — it brought us closer as a team today, I think — but it's never going to be easy."

NOTES: Chiefs CB Brandon Flowers (hamstring), S Abe Elam (left leg) and LB Derrick Johnson (left hamstring) left the game with injuries. Carolina lost LB James Anderson (eye), Murphy (foot) and S Sherrod Martin (right knee) during the game. ... Chiefs WR Dwayne Bowe caught four passes to move into third place in franchise history with 413 catches. ... Carolina has attempted 11 FGs this season.

___

Online: http://pro32.ap.org/poll and http://twitter.com/AP_NFL

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Unboxed: Stand-Up Desks Gaining Favor in the Workplace

THE health studies that conclude that people should sit less, and get up and move around more, have always struck me as fitting into the “well, duh” category.

But a closer look at the accumulating research on sitting reveals something more intriguing, and disturbing: the health hazards of sitting for long stretches are significant even for people who are quite active when they’re not sitting down. That point was reiterated recently in two studies, published in The British Journal of Sports Medicine and in Diabetologia, a journal of the European Association for the Study of Diabetes.

Suppose you stick to a five-times-a-week gym regimen, as I do, and have put in a lifetime of hard cardio exercise, and have a resting heart rate that’s a significant fraction below the norm. That doesn’t inoculate you, apparently, from the perils of sitting.

The research comes more from observing the health results of people’s behavior than from discovering the biological and genetic triggers that may be associated with extended sitting. Still, scientists have determined that after an hour or more of sitting, the production of enzymes that burn fat in the body declines by as much as 90 percent. Extended sitting, they add, slows the body’s metabolism of glucose and lowers the levels of good (HDL) cholesterol in the blood. Those are risk factors toward developing heart disease and Type 2 diabetes.

“The science is still evolving, but we believe that sitting is harmful in itself,” says Dr. Toni Yancey, a professor of health services at the University of California, Los Angeles.

Yet many of us still spend long hours each day sitting in front of a computer.

The good news is that when creative capitalism is working as it should, problems open the door to opportunity. New knowledge spreads, attitudes shift, consumer demand emerges and companies and entrepreneurs develop new products. That process is under way, addressing what might be called the sitting crisis. The results have been workstations that allow modern information workers to stand, even walk, while toiling at a keyboard.

Dr. Yancey goes further. She has a treadmill desk in the office and works on her recumbent bike at home.

If there is a movement toward ergonomic diversity and upright work in the information age, it will also be a return to the past. Today, the diligent worker tends to be defined as a person who puts in long hours crouched in front of a screen. But in the 19th and early 20th centuries, office workers, like clerks, accountants and managers, mostly stood. Sitting was slacking. And if you stand at work today, you join a distinguished lineage — Leonardo da Vinci, Ben Franklin, Winston Churchill, Vladimir Nabokov and, according to a recent profile in The New York Times, Philip Roth.

DR. JAMES A. LEVINE of the Mayo Clinic is a leading researcher in the field of inactivity studies. When he began his research 15 years ago, he says, it was seen as a novelty.

“But it’s totally mainstream now,” he says. “There’s been an explosion of research in this area, because the health care cost implications are so enormous.”

Steelcase, the big maker of office furniture, has seen a similar trend in the emerging marketplace for adjustable workstations, which allow workers to sit or stand during the day, and for workstations with a treadmill underneath for walking. (Its treadmill model was inspired by Dr. Levine, who built his own and shared his research with Steelcase.)

The company offered its first models of height-adjustable desks in 2004. In the last five years, sales of its lines of adjustable desks and the treadmill desk have surged fivefold, to more than $40 million. Its models for stand-up work range from about $1,600 to more than $4,000 for a desk that includes an actual treadmill. Corporate customers include Chevron, Intel, Allstate, Boeing, Apple and Google.

“It started out very small, but it’s not a niche market anymore,” says Allan Smith, vice president for product marketing at Steelcase.

The Steelcase offerings are the Mercedes-Benzes and Cadillacs of upright workstations, but there are plenty of Chevys as well, especially from small, entrepreneurial companies.

In 2009, Daniel Sharkey was laid off as a plant manager of a tool-and-die factory, after nearly 30 years with the company. A garage tinkerer, Mr. Sharkey had designed his own adjustable desk for standing. On a whim, he called it the kangaroo desk, because “it holds things, and goes up and down.” He says that when he lost his job, his wife, Kathy, told him, “People think that kangaroo thing is pretty neat.”

Today, Mr. Sharkey’s company, Ergo Desktop, employs 16 people at its 8,000-square-foot assembly factory in Celina, Ohio. Sales of its several models, priced from $260 to $600, have quadrupled in the last year, and it now ships tens of thousands of workstations a year.

Steve Bordley of Scottsdale, Ariz., also designed a solution for himself that became a full-time business. After a leg injury left him unable to run, he gained weight. So he fixed up a desktop that could be mounted on a treadmill he already owned. He walked slowly on the treadmill while making phone calls and working on a computer. In six weeks, Mr. Bordley says, he lost 25 pounds and his nagging back pain vanished.

He quit the commercial real estate business and founded TrekDesk in 2007. He began shipping his desk the next year. (The treadmill must be supplied by the user.) Sales have grown tenfold from 2008, with several thousand of the desks, priced at $479, now sold annually.

“It’s gone from being treated as a laughingstock to a product that many people find genuinely interesting,” Mr. Bordley says.

There is also a growing collection of do-it-yourself solutions for stand-up work. Many are posted on Web sites like howtogeek.com, and freely shared like recipes. For example, Colin Nederkoorn, chief executive of an e-mail marketing start-up, Customer.io, has posted one such design on his blog. Such setups can cost as little as $30 or even less, if cobbled together with available materials.

UPRIGHT workstations were hailed recently by no less a trend spotter of modern work habits and gadgetry than Wired magazine. In its October issue, it chose “Get a Standing Desk” as one of its “18 Data-Driven Ways to Be Happier, Healthier and Even a Little Smarter.”

The magazine has kept tabs on the evolving standing-desk research and marketplace, and several staff members have become converts themselves in the last few months.

“And we’re all universally happy about it,” Thomas Goetz, Wired’s executive editor, wrote in an e-mail — sent from his new standing desk.

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Advertising: Ford Plan to Revive Lincoln Hinges on a New Brand

An unusual ad campaign features Abraham Lincoln, the president for whom the car brand is named.

DEARBORN, Mich. — In the fiercely competitive world of luxury cars, the Ford Motor Company’s Lincoln brand has long been stuck in the slow lane, with stodgy models, older buyers and a distinct lack of pizazz.

But Ford is determined to change that. On Monday, the company will announce upgraded customer service initiatives, a new brand name for Lincoln that plays down the Ford connection and an unusual advertising campaign that features Abraham Lincoln, the president for whom the brand is named.

Ford’s chief executive, Alan R. Mulally, will begin the rebranding effort at an event outside Lincoln Center in Manhattan — the first in a series of moves meant to reverse Lincoln’s seemingly perpetual state of decline.

Ford will formally rechristen the brand as the Lincoln Motor Company and introduce a television spot that begins with an image of Lincoln, stovepipe hat and all. The brand’s first Super Bowl commercial is in the works, as is a revamped Web site that links consumers to a Lincoln “concierge” who can arrange test drives or set up appointments at dealerships.

Mr. Mulally will also announce the on-sale date in early 2013 for the radically redesigned Lincoln MKZ sedan, as well as plans for three new vehicles down the road.

If it seems like an all-out grab for attention, well, that’s exactly the point, said James D. Farley Jr., Ford’s head of global sales and marketing and the newly named chief of the Lincoln revival effort.

“The most important thing is for people to be aware that there is a transition going on,” Mr. Farley said. “We have to shake them up.”

The shake-up is long overdue and critically important to Ford, the nation’s second-largest car company behind General Motors.

As recently as the 1990s, Lincoln was the top-selling luxury automotive brand in the United States. Its large Town Car sedan and hulking Navigator S.U.V. defined the brand, and sales topped more than 230,000 vehicles a year.

But since then, Lincoln has been left in the dust by the German category leaders BMW and Mercedes-Benz, and Toyota’s Lexus division. This year, Lincoln ranks eighth in the American luxury segment, with sales down 2 percent, to 69,000, vehicles in the first 10 months of the year.

Its crosstown rival G.M. has had much better success reviving its Cadillac brand.

“Cadillac has been stabilized, but Lincoln is still muddling about,” said Jack Trout, president of the marketing firm Trout and Partners. “The big question is, how can Lincoln convince people it is more than just a gussied-up Ford?”

That task has now fallen to Mr. Farley, who left Toyota five years ago to join Ford just as Mr. Mulally’s transformation of the company was under way. Since then, Ford has introduced a succession of sleeker, more fuel-efficient and technology-laden models that have lifted sales and made it among the most profitable car companies in the world.

Lincoln, however, has not benefited from the turnaround. It accounts for only 3 percent of Ford’s total sales, down from 8 percent during the brand’s heyday. And since Ford has sold off foreign luxury divisions like Volvo and Jaguar, Lincoln is the sole upscale brand in the company.

“There is nothing more frustrating for us than to have someone who loves their Ford car and S.U.V., but goes out to buy a luxury model from another brand because we don’t have one,” Mr. Farley said.

The Lincoln comeback effort starts with the midsize MKZ, which has been redesigned with a sweeping grille, tapered body style and an all-glass retractable roof. It will be followed by three other new models, including a larger sedan and S.U.V.

But the brand’s image needs much more than better cars. Under Mr. Farley’s direction, a newly formed team of 200 people is intent on establishing the Lincoln Motor Company as a boutique luxury line known for personalized service.

Every customer who reserves an MKZ, for example, will be presented with an elegant gift upon receiving the car. Choices include a selection of wines and Champagne, custom-made jewelry or sunglasses, or a one-night stay at a Ritz-Carlton hotel.

Lincoln’s Web site will also have a consultant available 24 hours a day for live discussions about the products and to streamline the buying process. Prospective buyers will be given an opportunity for a “date night” with Lincoln, which includes a two-day test drive and a free meal at a restaurant.

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